Memory of a Killer, the new ten-episode thriller starring Patrick Dempsey, alongside Michael Imperioli, will be available exclusively on Prime Video in the UK and Ireland from 5th February 2026.
Inspired by the book and 2003 award-winning Belgian film De Zaak Alzheimer, Memory of a Killer is a dramatic thriller starring Emmy nominee Patrick Dempsey (Grey’s Anatomy, Dexter: Original Sin, Ferrari), Angelo Flannery/Doyle, who leads a dangerous double life while hiding an even deadlier personal secret, he is slowing losing his memory. Angelo lives two totally separate lives – as Angelo Doyle he is a fearsome New York City hitman and as Angelo Flannery he is mild-mannered upstate Cooperstown photocopier salesman and devoted father and widower. To further complicate things, he discovers that his wife’s recent death may not have been an accident. When someone comes after his pregnant daughter Maria it’s clear the wall between his lives has been breached. Angelo must stop whoever’s coming for his family by searching his past hits for clues, and the list is very long. Memory of a Killer is a redemptive story about a man who is losing his memory but gaining a conscience.

Emmy winner Michael Imperioli (The White Lotus, The Sopranos) stars opposite Dempsey in the role of Dutch Forlanni, an accomplished Italian chef whose restaurant is a front for criminal enterprise. As ruthless and mercurial as he is affable, Dutch is Angelo’s oldest friend, as well as his employer – he gives Angelo the targets for his hits. In a business as dangerous as theirs, Angelo must trust Dutch. But being trustworthy isn’t one of Dutch’s more dependable qualities.
The brand new series will launch with a two-episode premiere, followed by weekly episodes. Catch up on all of the latest Prime Video news right here.